Хирургические варианты лечения рака шейки матки в Индии

Cervical cancer, a prevalent yet preventable disease, stands as a significant health challenge for women worldwide. In India, where medical advancements are continuously evolving, understanding the surgical treatments available is crucial. This blog delves into the surgical options for cervical cancer treatment in India, highlighting how treatments vary based on cancer stages and the latest developments in minimally invasive surgeries.

Surgery plays a pivotal role in cervical cancer treatment, especially in the early stages. The choice of surgical method is influenced by the cancer's stage, the patient's age, and overall health. The goal is always twofold: eradicate the cancer and minimize the impact on the patient’s quality of life.

When is Surgery Performed?

• Early Detection (Stages 0-I): Surgery is often the first line of treatment. It's usually performed soon after diagnosis, provided the patient is medically fit for the procedure.
• Advanced Stages (Stages II-IV): Surgery might be combined with other treatments like chemotherapy or radiation. It's generally scheduled after these therapies shrink the tumor size, making the surgery more effective.

Early-Stage Cervical Cancer Treatment:

A. Cone Biopsy (Conization)

A cone biopsy, known medically as conization, is a surgical procedure that involves removing a cone-shaped section of the cervix. This part of the cervix is where the endocervical canal meets the ectocervix and is often the site of abnormal cellular changes. The procedure is usually performed under general anesthesia and can be done using one of several methods, such as a surgical scalpel, a laser, or the loop electrosurgical excision procedure (LEEP). The choice of method depends on various factors, including the extent of the abnormality and the physician's expertise.

A Cone Biopsy is recommended when there is a need for a more substantial tissue sample than what can be obtained through other cervical screenings. It is typically performed in cases of high-grade cervical dysplasia, when abnormal cells are widespread or when cancer cannot be ruled out based on previous test results.

What happens during the procedure:

1. Preparation: The patient is positioned similarly to a pelvic exam. Local anesthesia is administered to numb the cervix.

2. Speculum Insertion: A speculum is inserted into the vagina to provide access to the cervix.

3. Cone-Shaped Tissue Removal: Using a scalpel or a loop electrode, a cone-shaped piece of cervical tissue is carefully removed. The depth and width of the cone may vary depending on the medical indication.

4. Hemostasis and Closure: Any bleeding vessels are cauterized or stitched to control bleeding, and the remaining tissue is closed.

5. Recovery: The patient may experience mild cramping and discharge after the procedure. Rest and limited physical activity may be advised for a brief period.

6. Post-Procedure Care: The removed tissue is sent to a laboratory for examination, which determines the presence of abnormal cells, precancerous changes, or cancer. Follow-up care and treatment, if needed, are based on these results.

A Cone Biopsy is a crucial diagnostic and therapeutic procedure, as it allows for more comprehensive examination and treatment of cervical abnormalities, helping to prevent the progression of potential cancerous conditions.

B. Loop Electrosurgical Excision Procedure (LEEP)

The Loop Electrosurgical Excision Procedure (LEEP) is a widely used treatment method for addressing abnormal cervical cells, particularly in the early stages of cervical cancer. This procedure involves the use of a thin wire loop that is heated by electric current. The heated loop is then used to excise or cut away abnormal cells and tissue from the cervix.

The Loop Electrosurgical Excision Procedure (LEEP), also known as a LEEP biopsy, is performed to diagnose and treat abnormal cervical cells, typically detected during a Pap smear or colposcopy. The primary purposes of LEEP are to remove or obtain a biopsy of abnormal tissue and to prevent the progression of these cells into cervical cancer.

What happens during the procedure:

1. Preparation: The patient is positioned on the examination table, similar to a pelvic exam. The healthcare provider cleans the cervix and may administer local anesthesia to numb the area.

2. Insertion of Speculum: A speculum is inserted into the vagina to hold it open, allowing clear visualization of the cervix.

3. Acetic Acid Application: A weak solution of acetic acid (vinegar) may be applied to the cervix to highlight abnormal areas.

4. Placement of LEEP Instrument: A thin wire loop with an electrical current running through it is carefully positioned around the abnormal tissue on the cervix. This loop serves as both a cutting and cauterizing tool.

5. Tissue Removal: The healthcare provider uses the loop to remove the abnormal tissue or obtain a biopsy sample. The electrical current cuts and seals blood vessels to minimize bleeding.

6. Cauterization: After tissue removal, the loop is used to cauterize the remaining tissue to reduce the risk of bleeding and infection.

7. Speculum Removal: The speculum is removed, and the procedure is completed.

8. Recovery: The patient may experience some mild cramping and discharge following the procedure. Rest and avoidance of strenuous activities may be recommended for a short period.

9. Post-Procedure Care: The removed tissue is sent to a laboratory for further analysis. The results will determine whether further treatment or monitoring is needed.

LEEP is a relatively quick and effective procedure for diagnosing and treating cervical abnormalities. It helps prevent the progression of abnormal cells into cervical cancer and can be an essential part of a woman's reproductive health care.

Advanced-Stage Cervical Cancer:

C. Trachelectomy: A Fertility-Sparing Surgical Option for Cervical Cancer

Trachelectomy is a surgical procedure specifically designed for women with early-stage cervical cancer who wish to preserve their fertility. The surgery involves the removal of the cervix, the part of the uterus that opens into the vagina, while leaving the uterus itself intact. This approach is particularly beneficial for women who wish to conceive in the future.

Trachelectomy is considered when cervical cancer is diagnosed at an early stage, typically Stage I, and when the patient desires to preserve her fertility. It is a suitable option for women who wish to have children in the future and have not yet completed their family planning.

What happens during the procedure:

1. Preparation: The patient is placed under general anesthesia, rendering her unconscious and pain-free during the surgery.

2. Access to the Cervix: The surgeon makes an incision in the abdomen, either through a minimally invasive laparoscopic approach or traditional open surgery, to access the pelvic area.

3. Cervical Removal: The cervix is carefully removed while preserving the upper part of the uterus. This procedure may involve removing nearby lymph nodes to determine the extent of cancer spread.

4. Uterine Stitching: The upper part of the uterus is then stitched to the vagina to maintain support and function.

5. Recovery: After the surgery, patients may experience some discomfort and are typically monitored in the hospital for a short period. The recovery process varies but may take several weeks, with follow-up appointments to monitor healing and cancer status.

6. Post-Procedure Care: Depending on the pathology results and the extent of cervical cancer, further treatment options, such as radiation therapy or chemotherapy, may be considered to reduce the risk of cancer recurrence.

A trachelectomy offers women diagnosed with early-stage cervical cancer an opportunity to preserve their fertility while effectively treating the cancer. It provides a balance between cancer management and the desire to have children, making it a valuable surgical option for select patients.

D. Hysterectomy: A Comprehensive Surgical Approach for Cervical Cancer

A hysterectomy is a surgical procedure that involves the removal of the uterus and is a common treatment for cervical cancer. Depending on the extent of cancer spread and the patient's individual health situation, the procedure can vary, ranging from partial to radical.

Types of Hysterectomy

• Partial Hysterectomy (Supracervical Hysterectomy): This involves removing only the upper part of the uterus, leaving the cervix in place. It's less common for cervical cancer treatment.
• Total Hysterectomy: The entire uterus, including the cervix, is removed. This is the most common type of hysterectomy performed for cervical cancer.
• Radical Hysterectomy: This is the most extensive form, involving the removal of the entire uterus, cervix, part of the vagina, and surrounding tissues, including lymph nodes. It's typically performed when cervical cancer is more advanced.

A hysterectomy is typically recommended for cervical cancer when the disease has advanced beyond the early stages, when fertility preservation is not a priority, or when other treatment options have not been successful. The decision to perform a hysterectomy depends on factors such as the stage of cancer, the patient's overall health, and the extent of disease progression.

What happens during the procedure:

1. Preparation: The patient is placed under general anesthesia to ensure unconsciousness and pain relief during the surgery.

2. Incision and Access: The surgeon makes an incision, either in the abdomen (abdominal hysterectomy) or through the vaginal canal (vaginal hysterectomy), to gain access to the pelvic area.

3. Uterus and Cervix Removal: The uterus, including the cervix, is carefully removed from the body. In some cases, nearby structures, such as the fallopian tubes and ovaries, may also be removed, depending on the extent of the cancer.

4. Lymph Node Assessment: Nearby lymph nodes may be removed for examination to determine the extent of cancer spread.

5. Closure and Recovery: The incisions are closed, and the patient is closely monitored during the immediate postoperative period. Recovery times vary but may take several weeks.

6. Post-Procedure Care: Depending on the stage and extent of cervical cancer, additional treatments, such as radiation therapy or chemotherapy, may be recommended to prevent cancer recurrence.

A hysterectomy is a significant surgical intervention that effectively treats cervical cancer by removing the primary affected organs, the uterus and cervix. It is considered when other treatment options are not viable or when the disease has progressed beyond early stages, with the aim of eliminating cancer and preventing its return.

Advances in Minimally Invasive Surgeries in India: Laparoscopy and Robotic Surgery

a. Laparoscopy

Laparoscopy, a technique that has seen a significant rise in usage across Indian hospitals, is a minimally invasive surgical method revolutionizing the approach to treating cervical cancer. The procedure involves making small incisions in the abdomen to insert a laparoscope – a thin tube equipped with a camera – along with other surgical instruments. This technique is primarily utilized for staging, diagnosing, and in some cases, treating cervical cancer. The benefits of laparoscopy are manifold. It leads to considerably less pain for the patient, results in shorter hospital stays, ensures quicker recovery, and leaves smaller scars compared to traditional open surgery.

The adoption of laparoscopy in India has been remarkable, making it a common approach for a variety of surgical needs, including those related to cancer. This shift towards less invasive surgical techniques reflects the ongoing advancements in the Indian healthcare system and its commitment to adopting modern medical practices.

b. Robotic Surgery

Parallel to the growth of laparoscopy, robotic surgery has been making strides in the Indian medical landscape. This advanced technique involves surgeons using a computer to precisely control robotic arms that perform the surgery. The indications for robotic surgery in the context of cervical cancer are particularly for complex procedures, such as radical hysterectomies. The benefits it brings are significant: enhanced precision during surgery, reduced blood loss, faster recovery times, and less post-operative pain for patients.

The growth of robotic surgery in India is noteworthy, especially in urban and high-tech healthcare facilities. Indian medical centers are increasingly embracing this technology for its ability to improve patient outcomes, highlighting the country's progress in integrating cutting-edge medical technologies into its healthcare system.

The advancement of minimally invasive surgeries like laparoscopy and robotic surgery in India marks a pivotal shift in medical treatment approaches, particularly for complex conditions like cervical cancer. These techniques not only improve patient comfort and recovery but also signify the country's dedication to incorporating advanced medical practices and technologies.